Results: The mean age of men completing the study was 25 years (range, 23–33 years). In addition to the standard semen analysis, markers of sperm DNA quality were assessed. Semen samples were collected at the beginning of the study (day 1) and then on days 3, 7 and 14. Methods: Twenty normal men were recruited for daily ejaculation over 14 consecutive days, after a 3–5 days abstinence period. Although a significant number of articles have examined how the length of abstinence affects these semen analysis, the effects of frequent (daily) ejaculation has not been rigorously studied. Köhler 5ġDivision of Urology, Albany Medical College, Albany, NY 12208, USA 2Albany Stratton Veterans Affairs Medical Center, Albany, NY 12208 USA 3The Urological Institute of Northeastern New York, Albany, NY 12208, USA 4OSF Healthcare, Peoria, Illinois 61615, USA 5Division of Urology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA 6Division of Clinical Research, ReproSource Inc., Woburn, MA 01801, USA 7Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY 12208, USA 8Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794, USAĬontributions: (I) Conception and design: AD Benson, TS Köhler (II) Administrative support: AD Benson, L Frederick, B Leader, M McAsey, TS Köhler (III) Provision of study materials or patients: AD Benson, L Frederick, J Kontio, M McAsey, TS Köhler (IV) Collection and assembly of data: C Welliver, AD Benson, L Frederick, B Leader, E Tirado, P Feustel, M McAsey, TS Köhler (V) Data analysis and interpretation: C Welliver, AD Benson, L Frederick, B Leader, E Tirado, P Feustel, TS Köhler (VI) Manuscript writing: All authors (VII) Final approval of manuscript: All authors.īackground: Timed and frequent intercourse around the time of female ovulation is recommended to improve conception. Benson 4, Luke Frederick 5, Benjamin Leader 6, Edna Tirado 6, Paul Feustel 7, James Kontio 8, Mary McAsey 8, Tobias S.

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